AffiAB® UBP6 Rabbit Polyclonal Antibody

Catalytic activity: Ubiquitin C-terminal thioester + H (2)O = ubiquitin + a thiol. Disease: Involved in tumorigenesis. function: Has an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. In vitro, isoform 2, but not isoform 3, shows deubiquitinating activity. miscellaneous: The USP6 gene only exists in the primate lineage. similarity: Belongs to the peptidase C19 family. similarity: Contains 1 Rab-GAP TBC domain. tissue specificity: Testis specific. Expressed in various cancer cell lines.