AffiAB® HSP105 Rabbit Polyclonal Antibody

Function: Prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities. PTM: Phosphorylation on Ser-509 may be important for regulation of the HSPA8/HSC70 chaperone activity. similarity: Belongs to the heat shock protein 70 family. subunit: Interacts with HSPA8/HSC70. tissue specificity: Highly expressed in testis. Present at lower levels in most brain regions, except cerebellum. Overexpressed in cancer cells.