AffiAB® DECR2 Rabbit Polyclonal Antibody

Catalytic activity: Trans-2, 3-didehydroacyl-CoA + NADP (+) = trans, trans-2, 3, 4, 5-tetradehydroacyl-CoA + NADPH. function: Auxiliary enzyme of beta-oxidation. Participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. Catalyzes the NADP-dependent reduction of 2, 4-dienoyl-CoA to yield trans-3-enoyl-CoA. Has activity towards short and medium chain 2, 4-dienoyl-CoAs, but also towards 2, 4, 7, 10, 13, 16, 19-docosaheptaenoyl-CoA, suggesting that it does not constitute a rate limiting step in the peroxisomal degradation of docosahexaenoic acid. similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family. similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2, 4-dienoyl-CoA reductase subfamily.