Function: Protects against apoptosis mediated by Apaf-1. subcellular location: Associated with intracellular membranes. subunit: Binds Apaf-1, BCL-2 and BAD (Bcl-xl). tissue specificity: Highly expressed in testis, ovary, thymus, prostate, spleen, small intestine, colon, heart, skeletal muscle, liver, kidney and pancreas.