AffiAB® CD57 Antibody

SensiStain Anti-CD57 Antibody is a valuable tool for the identification of human CD57. Cluster of differentiation 57 (CD57), also known as NK-1, is a member of the glucuronyltransferase gene family. CD57 is an antigen found in natural killer cells, some T-lymphocytes, peripheral blood mononuclear cells, myeloid cells, and a variety of polypeptides as well as chondroitin sulfate proteoglycans. CD57 is a biomarker for tumours of neuroendocrine origin, including: paragangliomas, pheochromocytomas, and medulloblastomas. CD57 is also indicated as marker for a variety of neural tumours including: schwannomas, neurofibromas, and granular cell tumours. Anti-CD57 can be used to distinguish large B-cell lymphomas, T-cell lymphomas, and follicular lymphomas from Hodgkin’s lymphoma, a nodular lymphocyte-predominant neoplasm.