AffiAB® ROBO4 Rabbit Polyclonal Antibody

Function: Receptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning. May mediate the inhibition of primary endothelial cell migration by Slit proteins. similarity: Belongs to the immunoglobulin superfamily. ROBO family. similarity: Contains 2 fibronectin type-III domains. similarity: Contains 2 Ig-like C2-type (immunoglobulin-like) domains. subunit: Interacts with SLIT2 and ENAH. tissue specificity: Specifically expressed in endothelial cells. Expressed at sites of angiogenesis in different tumor types.