Cluster of Differentiation 38 (CD38) is an ontogenesis marker in T-cells which is also expressed in erythrocytes, platelets, prostate epithelial cells, islet cells, smooth and striated muscle cells, renal tubules, and retinal ganglial cells. CD38(+) stained B-cells are mainly present in germinal centers of secondary lymphoid organs, while the marginal zone is usually negative.