Function: Elicits growth inhibition on melanoma cells in vitro as well as some other neuroectodermal tumors, including gliomas. PTM: May possess two intramolecular disulfide bonds. similarity: Belongs to the MIA/OTOR family. similarity: Contains 1 SH3 domain. tissue specificity: All malignant melanoma cell lines tested and infrequently in glioma cell lines.