AffiAB® VPS26B Rabbit Polyclonal Antibody

Function: Probable component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. similarity: Belongs to the VPS26 family. subcellular location: Does not localize to endosomes. subunit: Probable component of the retromer complex composed of VPS26 (VPS26A or VPS26B), VPS29, VPS35, SNX1 and SNX2. Interacts directly with VPS35.